COLLEGE OF SCIENCE
GRADUATE INSTITUTE OF LIFE SCIENCES
Degrees Offered: M.S.
Chair: Wang, San-lang
The Institute
The Graduate Institute of Life Sciences was established in 2003 to offer a variety of graduate programs in the "post-genomic" era. The courses covering a diverse spectrum include cell biology, biochemistry, molecular biology, microbiology, cancer biology, bioinformatics, structural biology, genomics and proteomics to provide each graduate with the intellectual background, laboratory skills, and research experience necessary to be successful in his/her future scientific endeavors. Meanwhile, students will undergo an intensive in-depth course work schedule interspersed with research projects.
Faculty
Professors
Chang, Yue-cune; Chien, Su-fang; Lee, Shih-yuan; Wang, San-lang; Zhou, Zi-cong
Assistant Professors
Chen, Ming-kai ; Chen, Yau-hung ; Chuang, Tzu-chao ; Lee, Chang-shin ; Wu Chun-hung
Degree Requirements
The Graduate Institute of Life Sciences offers a master's program for college level graduates with an interest and passion for life sciences. Requirements for a Master's degree in Science: Successful completion of 24 credits of courses, including 8 credits of required courses and 4 credits of Seminar. Students are also required to submit a written master's thesis completed under the supervision of a faculty member, and pass an oral Examination.
Course Descriptions
Master's Program
E0098 Microbiology (3/0) Prokaryotic Cells, Eukaryotic Cells, Viruses, Microbial Control, Microbial Genetics, Genetic Engineering, Infection and Disease, Immunity, Environmental and Applied Microbiology.
S0072 Biotechnology (0/3) DNA Technique, Genetic Modified Food and Transgenic Plant, Application of Transgenic Animal, Animal Cloning, Stem Cell, Gene Therapy, Biochip, Genetic Project.
S0207 Advanced Biochemistry (0/3) Biomolecules, Mechanisms of Enzyme Action, Metabolism, Expression and Transmission of Genetic Information.
S0514 Advanced Organic Chemistry (3/0) Chemical Bonding, Molecular Structure and Orbital, Stereo Chemistry and Conformation Analysis, Linear Free Energy Relationship, Kinetic Isotope Effects.
S0605 Utilization of Bioresources (3/0) This course aims at discussing the bioconversion and utilization of bioresources and introducing special processing techniques developed currently.
S0776 Bioinformatics (3/0) Biological Databases, Sequence Similarity Search, Multiple Sequence Alignment, Advanced Pattern Search, Sequence Annotation, Structure Bioinformatics, Protein Structure Prediction, Microarray Data Analysis, Proteomic Data Analysis, Systems Biology, Cheminformatics and Pharmaceutical Informatics, Tissue Informatics.
S0777 Molecular Biology (3/0) Brief history. Structure and chemistry of DNA, Techniques of cloning, Common techniques used by molecular biologists, Transcription in prokaryotes, Transcription in eukaryotes, Post-transcriptional events, Translation process in both prokaryotes and eukaryotes, Mechanisms of DNA replication, recombination, repair, translocation, Briefs in genomics.
S0778 Lecture Series on Life Sciences (2/0) Advanced lectures on specific fields of life sciences by invited expert speakers.
S0787 Environmental Biology (0/3) Cells, Evolution and Ecology, Environmental Hormones, Environmental Microbiology.
S0788 Genomics (0/3) Large-scale analysis of DNA sequence, Genetic mapping, Physical mapping, Genome Projects of Model Organisms, Gene Content and Organization, Finding genes and mutations. Link between Genotypes and Phenotypes, Sequence-specific manipulation of DNA.
S0798 Developmental Biology (3/0) This course introduces the basic concepts of cell-cell interaction,
early development, late development and organogenesis. This course will make graduate students
understand the mystery of life.
S0799 Cancer Biology (0/3) This course focuses on the basic concepts of carcinogenesis, including physical, chemical and genetic factors that are involved during carcinogenesis.
S0789 Protein Chemistry (0/3) Protein biosynthesis, Protein expression, Chemical and physical
properties of amino acids, peptides and proteins, Chemical modification, Post-translational
modification, Protein engineering, Peptide mapping, The Edman-degradation and related techniques,
Protein purification, Spatial organization of proteins, Protein folding, Structure function relationship,
Special topics: catalytic mechanisms of protein enzymes, prion proteins, protein arrays.
S0800 Transgenic Research (0/3) This course introduces the generation and application of
transgenic animals, including mice, chicken, pigs, and fish, enabling students to understand how to
generate a transgenic animal.
S0801 Introduction to Genetic Engineering (0/2) DNA, RNA and Protein Synthesis, Structure and
Function, Basic Techniques in Gene analysis, Vectors, Polymerase Chain Reaction, Cloning a Gene,
Gene Identification, Mutagensis, Protein Expression and Purification, Genome Sequencing,
Post-Genome Analysis, Engineering Plants, Engineering Animal Cells.
T0095 Seminar I (2/0) Skills for making a presentation, Skills for analyzing and reading a research paper.
T0096 Seminar II (0/2) Skills for making a presentation, Skills for analyzing and reading a research paper.
T8000 Thesis (0/4)
M1653 Biostatistics (3/0) Exploratory Data Analysis, Experimental Design and Data Analysis, Response Surface Method (RSM).
S0820 Cellular Biochemistry (0/3) The course will cover the following: the characteristics that are
common to most eukaryotic cells, including expression and transmission of genetic information; the
principles of the main experimental methods for investigating cells; internal organization of the cell;
behavior of cells in multi-cellular organisms, including cell-cell junctions, extra-cellular matrix and
pathogens and infection.

